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The obesity rate among children has tripled since 1960, with 32% of US children considered overweight or obese, and many of them suffering the same weight-related problems as adults: diabetes mellitus type 2, hypertension and cardiovascular disease. In the February issue of Archives of Pediatrics & Adolescent Medicine, a report by Darrell M. Wilson, M.D., of Stanford University and the Lucile S. Packard Children’s Hospital, Stanford, Calif., along with colleagues in the Glaser Pediatric Research Network Obesity Study Group showed that teens given Metformin, a common pill given to type 2 diabetics, helped lower their BMI score. BMI is an indicator of body fat percentage—the lower your BMI the less risk you have for cardiovascular disease and other weight-related disorders.
The research group split 77 obese teenagers, ages 13 to 18, into two groups. Both groups were put on a “lifestyle intervention program” which included dietary changes and increased physical activity. One group received 2,000 mg of Metformin XR per day and the other group received a placebo. After 38 weeks, the kids receiving the Metformin XR showed a significantly lowered BMI than the teens receiving the placebo, even though all the teens were on the same diet and exercise plan. Unfortunately, once the drug was discontinued, the BMI in the teens previously taking Metformin again went up. This certainly lends credence to my long-held belief that Metformin can be an effective weight-management tool for some people.
In addition to helping with weight problems, Metformin works very similarly to Resveratrol and has significant anti-aging properties. Like Resveratrol, it helps regulate the Sirt-2 gene, helping protect DNA from damage, so it’s a very important product.
I think Metformin can be a helpful treatment for kids who are overweight. It will improve insulin resistance which will assist with weight loss, which is a great thing! Many of these overweight young kids have developed insulin resistance, so many of them do need this extra boost. Metformin can actually help some overweight teens avoid the development of type 2 diabetes, when used in conjunction with diet and exercise.
It’s not a magic pill, and you still need diet and exercise to get the best results, but this combination certainly shows promise.
Dr. Berger is a renowned leader in cosmetic and anti-aging medicine, bringing over 25 years of diverse medical experience to his practice. He earned his medical degree from the University of Ottawa and completed advanced training in Internal Medicine and Clinical Pharmacology at McGill University. Dr. Berger was board certified by the American Board of Emergency Medicine for two decades and is a diplomat of the American Board of Anti-Aging and Regenerative Medicine.
Throughout his distinguished career, Dr. Berger has developed expertise in clinical and medical management, pharmacology, nutraceuticals, emergency medicine, cosmetic surgery, cosmetic medicine, anti-aging, holistic, and regenerative medicine. Dr. Berger’s unique approach blends traditional Western medical training with integrative and preventative therapies, including Eastern Medicine. He is passionate about helping patients achieve both inner health and outer beauty, believing that a balance of anti-aging medicine and non-surgical cosmetic therapies is key to emotional, physical, and mental well-being. By combining the latest medical advancements with holistic care, Dr. Berger empowers his patients to look and feel their best, while also focusing on prevention and long-term wellness.
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